Pseudomonas aeruginosa producing beta metalloenzyme (VIM, NDM): A case report
1 Microbiology Laboratory, Ibn Tofail Hospital, MOHAMMED VI University Hospital, Faculty of Medicine and Pharmacy, Marrakech, Morocco.
2 Department of Trauma and Orthopaedics, Ibn Tofail Hospital, MOHAMMED VI University Hospital, Marrakech, Morocco.
Case Study
GSC Advanced Research and Reviews, 2024, 20(03), 207–211.
Article DOI: 10.30574/gscarr.2024.20.3.0344
Publication history:
Received on 10 August 2024; revised on 20 September 2024; accepted on 23 September 2024
Abstract:
Pseudomonas aeruginosa is an opportunistic bacterium with a high rate of acquisition of new resistance. The production of metallo-ß-enzyme is a resistance mechanism that is still relevant today. We report the case of a diabetic patient presenting with a trauma to the lower limb; the patient underwent immediate surgery, a discharge of pus was marked in the evolution; the bacteriological profile was in favour of a strain of Pseudomonas aeruginosa producing type VIM metallo carbapenemase, with a positive EDTA synergy test and a positive carba test. Despite repeat surgery, the introduction of antibiotic therapy, treatment and control of the glycaemic cycle, the evolution was unfavourable, threatening the vitality of the limb.
Keywords:
Pseudomonas aeruginosa; Multi-resistant bacteria; Beta metalloenzyme; EDTA synergy test; Rapid carbapenemase detection test
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