Changes of the endothelial properties in patients with coronary artery disease after COVID-19
Republican Specialized Scientific Practical Medical Center of Therapy and Medical Rehabilitation, Tashkent, Uzbekistan.
Review Article
GSC Biological and Pharmaceutical Sciences, 2022, 21(02), 269-273.
Article DOI: 10.30574/gscbps.2022.21.2.0440
Publication history:
Received on 12 October 2022; revised on 21 November 2022; accepted on 23 November 2022
Abstract:
COVID-19, like other respiratory viruses, has extra pulmonary manifestations. Like other organs cardiovascular system suffers from the virus. In particular, exposure to the virus leads to damage to the cardiovascular system (CVS), the pathophysiological mechanisms of which are not completely clear; a full understanding of the mechanisms of interaction between COVID-19 and CVS has not been formed. The article analyzes current ideas about COVID-19, considers possible links in pathogenesis, attempts to systematize the pathophysiological mechanisms of CVS damage and their complications, analyzes the relationship with cardiovascular comorbidity, and describes the features of pathomorphology and a hypothetical long-term prognosis. The presented information can contribute to understanding the two-way interaction of cardiovascular diseases and the effects of COVID-19 in order to develop effective preventive measures and make the right decision in choosing a therapeutic tactic for a patient within a systematic approach.
Keywords:
Cardiovascular system; Pathogenesis of COVID-19 damage; Angiotensin-converting enzyme-2; Renin-angiotensin system; Endothelial dysfunction; Microcirculation; Hemostasis system
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Copyright © 2022 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
