The effect of curcumin after high-intensity exercise (HIE) on blood glucose levels

Sabila Camelia Hidayat 1, *, Sundari Indah Wiyasihati 2, Lina Lukitasari 2 and Lilik Herawati 2

1 Medical Programee, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
2 Department of Medical Physiology and Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
 
Review Article
GSC Biological and Pharmaceutical Sciences, 2024, 29(03), 022–026.
Article DOI: 10.30574/gscbps.2024.29.3.0443
Publication history: 
Received on 14 October 2024; revised on 03 December 2024; accepted on 06 December 2024
 
Abstract: 
Background: After high-intensity exercise (HIE), which is widely used because it can build muscle mass more quickly, muscles use a lot of energy, leading to significant gluconeogenesis, and an increase in glucose production. Curcumin, the active compound in turmeric, is well-known as an anti-inflammatory agent that can potentially to regulate blood glucose. This review aims to determine the impact of curcumin consumption after HIE on glucose levels.
Method: This literature review use searching strategy for articles, journals, and books in research journal database. The database were taken from Pubmed and MDPI. The keyword were curcumin, HIE, and glucose. This literature review using 24 scientific articles as online data sources which were then further analyzed.
Results and Discussion: Curcumin may help lower the rise in blood sugar after high-intensity exercise by blocking NF-κB, which lowers TNF-α levels. However, curcumin did not effectively manage short-term blood sugar changes in overweight or have prediabetes or metabolic syndrome populations.
Conclusion: Curcumin potentially regulate blood glucose after HIE.
 
Keywords: 
Curcumin; Glucose; High-intensity exercise; Blood glucose; Turmeric
 
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