Emerging approaches to genetic therapy in treatment for breast cancer
1 Faculty of Medicine and Nutrition, Universidad Juárez del Estado de Durango, Durango, Dgo. México.
2 Department of Genetics, Faculty of Medicine and Nutrition, Universidad Juárez del Estado de Durango, Durango, Dgo. México.
Review Article
GSC Biological and Pharmaceutical Sciences, 2024, 29(02), 414–419.
Article DOI: 10.30574/gscbps.2024.29.2.0453
Publication history:
Received on 20 October 2024; revised on 26 November 2024; accepted on 29 November 2024
Abstract:
Breast cancer is one of the leading causes of death among women, which implies an urgent need to explore further alternative therapeutic strategies than conventional surgery, chemotherapy, and radiotherapy treatments. Thus, prevention should be highlighted through early genetic screening, not only among patients with clear risk factors but also among the general population in order to discover predisposition and intervene earlier.
The current therapeutic innovations are focused on improving such treatments by devising less invasive and more specific approaches. Examples include gene repair, such as halting tumor growth by restoring functionality to damaged genes using CRISPR and similar technologies. MicroRNAs have also shown much promise in controlling major cancer processes such as metastasis and cell division. Besides, nanoparticle-based drug delivery allows for more effective release of drugs. Consequently, there is lesser development of side effects. Suicide gene therapy is also commanding more attention against breast cancer as a less aggressive and hence more effective therapy with the appearance of selective killing of cancerous cells.
Keywords:
Breast cancer; Gene therapy; Nanoparticle; mRNA vaccination
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
