Establishment of a bio-industry-need hemisection of spinal cord rat model
1 Department of Pet Healthcare, Yuanpei University of Medical Technology, Xiangshan, Hsinchu 300, Taiwan.
2 Division of Animal Industry, Animal Technology Research Center, Agricultural Technology Research Institute, Xiangshan, Hsinchu 300, Taiwan.
3 Department of Nursing, Yuanpei University of Medical Technology, Hsinchu 300, Taiwan.
# Contributed equally to this work.
Research Article
GSC Biological and Pharmaceutical Sciences, 2024, 26(03), 084–091.
Article DOI: 10.30574/gscbps.2024.26.3.0086
Publication history:
Received on 30 January 2024; revised on 10 March 2024; accepted on 13 March 2024
Abstract:
Spinal cord injury (SCI) is a severe central nervous system disorder, and due to its complex pathophysiology, effective treatment strategies are currently lacking, posing a significant challenge in the field of medicine. While research into the fundamentals of SCI continues to advance and innovate, there exists a gap between basic research and clinical applications, hindering the translation of basic research findings into clinical practice. One of the reasons for this gap is the use of non-standardized animal models for SCI, which leads to inaccuracies in research results and reduces the guidance value of basic research for clinical treatment. This study provides a SCI rat model for R&D of SCI medicine target research and therapeutic strategy designs.
Keywords:
Bio-industry; Central nervous system; Hemisection of Spinal Cord; Rat Model; Spinal Cord Injury
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