Evaluation of bioactivity of stem bark extracts of Lovoa trichiliodes (Harm) and Trichilia heudelotii Planc (Harm)
Department of Science Laboratory Technology, Rufus Giwa Polytechnic, Owo, Ondo State, Nigeria
* Corresponding author
Research Article
GSC Biological and Pharmaceutical Sciences, 2018, 02(01), 001–008
Article DOI: 10.30574/gscbps.2018.2.1.0019
Publication history:
Received on 16 September 2017; revised on 18 October 2017; accepted on 07 November 2017
Abstract:
This study evaluated the bioactivity of the stem bark extracts of Lovoa trichiliodes and Trichilia heudelotii using standard methods. The highest yield of 10.20% was obtained from the stem bark extract of T. heudelotii. Qualitative phytochemical examination of the plant extracts indicated the presence of different secondary metabolites which remarkably inhibited the growth of Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Enterococcus faecalis, Klebsiella pneumoniae, Salmonella typhii, Aspergillus flavus, Candida albicans and Candida glabrata. However, the cold water extract of L. trichiliodes exhibited no activity against the test pathogens. The highest mean (22.33±0.33 mm) zone of inhibition and minimum inhibitory concentration (MIC) of 2.5 mg/ml were exhibited by the acetone stem bark extract of L trichiliodes against B. subtilis ATCC6633. The results affirmed the traditional uses of the plants in the management and treatment of numerous diseases caused by the test pathogens.
Keywords:
Antimicrobial; Phytochemical; Infectious diseases; L. trichiliodes; T. heudelotii
Full text article in PDF:
Copyright information:
Copyright © 2018 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0.
