Phytochemical profiling of aqueous extract of Gnetum africanum stem bark using Gas Chromatography–Mass Spectrometry (GC-MS)
1 Department of Biochemistry, Kingsley Ozumba Mbadiwe University, Ideato, Imo State, Nigeria.
2 Department of Biochemistry, Federal University of Technology, Owerri, Imo State, Nigeria.
Research Article
GSC Biological and Pharmaceutical Sciences, 2024, 29(02), 356–363.
Article DOI: 10.30574/gscbps.2024.29.2.0451
Publication history:
Received on 15 October 2024; revised on 25 November 2024; accepted on 27 November 2024
Abstract:
The aqueous extract of stem bark of Gnetum africanum, was subjected to phytochemical screening using gas chromatography equipped with mass spectrometry (GC-MS). In this study gas chromatography mass spectrometry (GC-MS) analysis revealed the presence of remarkable natural bioactive components in methanol extract of Gnetum africanum. The major constituents are propofol, trimethylsilyl ether (9.72%), phenol, 2,6-bis(1,1-dimethylethyl)-4-(methoxymethyl)- (7.25), -4'-dimethylamino-2'-(trimethylsilyl) acetanilide (5.69%), 2,2,2-trifluoro-N-(3-(methylthio)phenyl)acetamide (5.48%), 4-(4-bromophenyl)pyridine (5.35%), 17.beta.-hydroxy-6-oxo-4,5-secoandrostan-4-oic acid methyl ester (5.17%), methaqualone (5.07%). The bioactive components in the aqueous extract of the stem bark of Gnetum africanum have favourable medicinal qualities such as antioxidant, antimicrobial, anti-inflammatory, anticancer, properties and also serve as an anesthetic and a sedative used in treatment of and neurological disorders. The phytochemical profiling of aqueous extract of Gnetum africanum using gas chromatography–mass spectrometry (GC-MS) revealed the presence of bioactive compounds with important therapeutic properties.
Keywords:
Vegetable; Gymnosperms; Bioactive components; Medicinal; Extracts; Analysis
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