Review of anatomical and histological alterations in the brain of patients with autism
Department of Anatomy, College of Medicine, University of Mosul, Mosul, Iraq.
Review Article
GSC Biological and Pharmaceutical Sciences, 2024, 26(03), 217–221.
Article DOI: 10.30574/gscbps.2024.26.3.0104
Publication history:
Received on 12 February 2024; revised on 23 March 2024; accepted on 26 March 2024
Abstract:
Autism spectrum disorder is a developmental illness which interferes with communication and behavior. autism can be detected at any age but symptoms become clinically evident in the first 2 years of life. The main symptoms are associated with social communication, interaction, monotonus actions and loss of enjoyment in objects and events. In addition it is linked to other psychological disorder like attention-deficit hyperactivity and epilepsy in the early years of life. Early diagnosis of the disorder with successive interference is very helpful to refine verbal outcomes and upgrade critical symptoms. Nowadays it is evident the neuroanatomical involvement in this disorder in early childhood and teenage groups like the cortical tissue of frontal, temporal and parietal lobes, amygdala and hippocampus, in the inferior cerebellar vermis and left cerebellar lobule.
In conclusion: Autism is a neurodevelopmental disorder which characterized by diminished communication skills, behavioral disturbances and cognitive impairment issues which definitely associated with neuroanatomical and microstructural changes in the brain cortex. In addition to genetic role in its etiology.
Keywords:
Autism; Brain; Neuroanatomy; Histology; Abnormalities
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