Drug design, discovery and development and their safety or efficacy on human body

Shamima Shultana, Kazi M Maraz, Arwah Ahmed, Tanzila Sultana and Ruhul A Khan *

Institute of Radiation and Polymer Technology, Atomic Energy Research Establishment, Savar, Dhaka, Bangladesh.
 
Review Article
GSC Advanced Research and Reviews, 2021, 17(02), 113–122.
Article DOI: 10.30574/gscbps.2021.17.2.0330
Publication history: 
Received on 07 October 2021; revised on 16 November 2021; accepted on 18 November 2021
 
Abstract: 
Drug Design, often mentioned as rational drug design or just rational design. It is defined as the study of the shape of molecules in order to determine how they will bind receptors on cells or combine with other molecules. It is based on molecular shape or architecture is an alternative to blindly testing hundreds of molecules to see if one or more of them will bind cellular or molecular targets. The drug is an organic molecule, when it is bind to target site it can either inhibit or activate the function of a bio-molecule which results in therapeutic benefit.
 
Keywords: 
Definition; Molecular target; Discovery; New drugs investigation; Clinical research; Clinical trials
 
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