Determination of hemoglobin level, mean cell volume and red cell distribution width among patients with renal failure in Khartoum state

Mohammed Abdelazeem Abdelghani 1, Abdalrahman Alnour Aldekem 1, Elharam Ibrahim Abdalla 1, *, Salam Elnour Mohamed 2, Salah Eldin Omer 2 and Abdelgadir Elamin Eltom 2, *

1 Department of Medical Laboratory Collage of Health Sciences, Alzaeim Alazhari University, Khartoum Bahri, Sudan.
2 Medical Laboratory Sciences, College of health sciences, Gulf Medical University, AL JURF, Ajman, United Arab Emirates.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2022, 20(01), 284–291.
Article DOI: 10.30574/gscbps.2022.20.1.0216
Publication history: 
Received on 30 May 2022; revised on 20 July 2022; accepted on 22 July 2022
 
Abstract: 
As a body fluid, blood supplies nutrients and oxygen to cells and carries away metabolic waste products. A cross-sectional study was conducted between February and April 2021 in Khartoum state to examine the effect of renal failure on hemoglobin level, mean cell volume (MCV), and red cell distribution width (RDW) in Sudanese patients. One hundred and thirty-five samples were collected from patients with renal failure, 100 of them were chronic, 35 were acute, and thirty 30 samples were from normal individuals as control, the age of patients between eighteen 18 and eighty 80 years, all the selected participants were not suffering from heart diseases or liver diseases.3 ml of venous blood samples were collected in ethylene diamine tetra acetic acid (EDTA) containers. The haemoglobin, MCV, and RDW were investigated using a haematological analyzer (Sysmex KX-21N).
The hemoglobin level was significantly low among patients with renal failure compared to normal individuals (P value=0.011). While no significant differences in mean cell volume (MCV) and red cell distribution width (RDW) between patients and normal individuals, with P-values (0.842) and (0.254) respectively. The study results reveal that the haemoglobin levels are lower in patients with kidney failure than in healthy individuals. Additionally, the haemoglobin levels decrease as the patient progresses into chronic renal failure in contrast to acute renal failure.
 
Keywords: 
Hemoglobin; Mean Cell Volume; Red Cell Distribution; Renal Failure
 
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Copyright information: 
Copyright © 2022 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0

 

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