Diabetic foot infection and its management: A review

Anette Paulson*, Krishna Kumar K, Panayappan L and Leo Mathew 

Department of Pharmacy Practice, St. James College of Pharmaceutical Sciences, Chalakudy, Kerala.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2018, 04(01), 019–024
Article DOI: 10.30574/gscbps.2018.4.1.0041
Publication history: 
Received on 24 May 2018; revised on 13 June 2018; accepted on 14 June 2018
 
Abstract: 
Diabetic foot infections are common in patients with diabetes which leads to hospitalization and it is the most frequent cause of non-traumatic lower extremity amputation. Diagnosis of foot infections based on clinical signs and symptoms of inflammation. Infected lesion culturing discloses the pathogen and their susceptibilities. The predominant pathogen responsible for infection is gram-positive cocci, especially Staphylococci and also Streptococci. Gram-negative bacilli and anaerobes are mainly found in chronic or previously treated wounds. The infected wounds require antibiotic therapy, the agents, and duration of treatment are predicted based in the severity of infection and initial management of diabetic foot infection should do by empirical therapy which based on the susceptibility data. Preventive measures to control diabetic foot infections are patient education on foot care, glycemic control, use of prescription footwear, intensive care from a podiatrist, and evaluation of surgical interventions indicated. This article explains about Pathophysiology classification, assessing the severity and treatment of diabetic foot infections.
Keywords: 
Diabetic foot infection (DFI); Diabetes; Infection
 
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