Prevalence and antibiotic susceptibility pattern of Uro-pathogens isolated from urine in a tertiary care hospital in Nigeria
1 Department of Surgery, Abubakar Tafawa Balewa University Teaching Hospital (ATBUTH), P.M.B 0117, Bauchi State, Nigeria.
2 Department of Medical Microbiology, Abubakar Tafawa Balewa University Teaching Hospital (ATBUTH), P.M.B 0117, Bauchi State, Nigeria.
3 Department of Laboratory Services, Abubakar Tafawa Balewa University Teaching Hospital (ABTUTH), P.M.B 0117, Bauchi State, Nigeria.
4 Department of Medical Microbiology, College of Medical Sciences Abubakar Tafawa Balewa University (ABTU) P.M.B 0117, Bauchi State, Nigeria.
Research Article
GSC Biological and Pharmaceutical Sciences, 2024, 28(03), 253–260.
Article DOI: 10.30574/gscbps.2024.28.3.0321
Publication history:
Received on 27 July 2024; revised on 12 September 2024; accepted on 14 September 2024
Abstract:
Urinary tract infections (UTIs) are one of the most common bacterial infections in humans both in the community and hospital setting. Urinary tract infection (UTI) is the most common health care -associated group of bacterial infection affecting humans in Africa. This study was done to evaluate the frequency of uropathogens isolated from urine and their susceptibility pattern in Abubakar Tafawa Balewa University Teaching Hospital (ATBUTH) Bauchi. A total of 373 urine samples from out-patients and hospitalized patients were studied. Samples were inoculated on Cystine Lactose Electolyte-deficient (CLED) agar. 165 isolates were obtained which were further identified by standard Microbiological methods. Antimicrobial Susceptibility pattern was studied by Kirby-Bauer’s disc diffusion method. UTIs were found more common in females 122(73.9%). Among the 165 uropathogens isolated from patients with UTI, the commonest isolate was E. coli (29.1%) followed by Klebsiella pneumoniae (15.8%) with the least Citrobacter spp. 1(0.6%). The overall prevalence of UTI in this study is 44.2%. Multidrug resistance was found to be significantly (P<0.05) more in uropathogens (77%). Monitoring of antimicrobial susceptibility testing are necessary to avoid treatment failure in patients with UTI.
Keywords:
Antibiotic; Uropathogens; Multidrug Resistance; Susceptibility; UTIs
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