Antibacterial activity of Solanum macrocarpon against clinically derived isolates of Streptococcus mutans from patients attending university of Maiduguri teaching hospital: Implantation of correlation analysis prior to mathematical and computational appro
1 Department of Microbiology, Faculty of Science, University of Maiduguri, PMB 1069, Maiduguri, Borno State, Nigeria.
2 Department of Medical biochemistry, Near East University, Nicosia, Turkish Republic of Northern Cyprus.
3 Rabiu Musa Kwankwaso College of advance and remedial studies, Tudunwada Kano, Nigeria.
4 Faculty of Clinical Sciences, Bayero University, Kano 700006, Nigeria.
Research Article
GSC Advanced Engineering and Technology, 2022, 03(02), 010–017.
Article DOI: 10.30574/gscaet.2022.3.2.0029
Publication history:
Received on 27February 2022; revised on 05 April 2022; accepted on 07 April 2022
Abstract:
Plants have been employed as herbal medicines in many parts of the world, and this tend to gain attention as complementary or alternative to modern medicines. This study is aimed to assess the antibacterial activity ofSolanum macrocarpon against Streptococcus mutans.
Standard microbiological and biochemical techniques were used to isolates and identify Streptococcus mutans. The Distilled water, Ethanol, Methanol extraction were performed on different part of Solanum macrocarpon and tested for antibacterial activity using the Agar well diffusion method. All the extracts inhibit the growth of Streptococcus mutans except distilled water extract with no or little effect. The results also showed an increase in antibacterial activity with increase in concentration21 mm at 100% concentration to 4 mm of the crude extracts. This study therefore revealed that Solanum macrocarponextract demonstrated greet inhibitory effect on the test organism. Thus, the result provides a basis for the traditional use of Solanum macrocarpon in cleaning teeth and toothache treatment.
Keywords:
Solanum macrocarpo; Streptococcus mutans; Antibacterial; hospital; Computational approach
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