Anti-tumor response of some natural products
Department of Biotechnology, Faculty of Agriculture (Abu-Naama) University of Sinnar. Sudan.
Research Article
GSC Advanced Research and Reviews, 2023, 17(02), 162–166.
Article DOI: 10.30574/gscarr.2023.17.2.0423
Publication history:
Received on 29 September 2023; revised on 12 November 2023; accepted on 15 November 2023
Abstract:
The role of natural products as asource for remedies has been recognized since ancient times. Many pharmaceutical agents have been discovered by screening natural products. This study will briefly summarize research on the study of antitumor effects of some plant natural products (Bee honey, Cumin extract, a combination of both at a rate of 1:1, Ginger extracts and Tepary beans Lectin). The crudes extract obtained by cold extraction were evaluated for antibacterial by using disc diffusion method and antitumor activity by using Agrobacterium tumefaciensstrain SDB0012 (local isolate ) as biological tool for potato disk bioassay technique. Results of Inhibition zone as antibacterial indicted that honey, cumin, their mixture, ginger extracts and lectin of Tepary bean have no anti-bacterial effects against the indigenous strain A.tumefaceins SDB0012. The Indigenous Strain of A.tumefaceins SDB0012facilitated use of the potato disc bioassay technique to study antitumor activity of tested natural products (bee honey, cumin extract, a combination of both at a rate of 1:1, Ginger extracts and Tepary bean Lectin). Screening for antitumor activity resulted in 40% 55% and 100% inhibition from the total surface of the potato disc due to application of honey, cumin oil and the mixture, respectively. lectin(Dark red kidney bean hemagglutinin ) also have antitumor activity. While Ginger methanol extract have largest result as antitumor 95% compare with author extracts of ginger.
Keywords:
Anti-tumor; Potato disk; Honey; Cumin oil; Ginger; Lectin
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
