Bio-efficacy of Karu Nochi, Vitex negundo L. (Lamiaceae) against the dengue vector, Aedes aegypti (L.)

Omvir Singh Chechi 1, Arvind Kumar 1, 2, Ramasamy Prabhu 3, Subramanian Manjula 3, Arokiasamy Reni Prabha 3, NG Tamil Selvi 4 and Jayapal Subramaniam 5, 6, *

1 Department of Zoology, Research and Development Centre, Bharathiar University, Coimbatore,Tamil Nadu-641046, India.
2 Department of Zoology, Janta Vedic College, Baraut, Baghpat-250611, Uttar Pradesh, India.
3 Department of Zoology, Chikkaiah Naicker College, Erode-638 004, Tamil Nadu, India.
4 Department of Zoology, Government Arts College, C. Mutlur, Chidambaram-608 102, Tamil Nadu, India.
5 Department of Zoology, School of Life Sciences, Bharathiar University, Coimbatore-641 046, Tamil Nadu, India.
6 RUSA 2.0-Bharathiar Cancer Theranostics Research Centre (BCTRC), Bharathiar University, Coimbatore-641046, India.
 
Research Article
GSC Advanced Research and Reviews, 2022, 11(01), 204–209.
Article DOI: 10.30574/gscarr.2022.11.1.0114
Publication history: 
Received on 22 March 2022; revised on 25 April 2022; accepted on 27 April 2022
 
Abstract: 
The dengue vector, Aedes aegypti (L.) is one of the world's deadliest species and it spreads diseases like Zika, chikungunya, dengue, and yellow fever. In this present investigation, we attempt to evaluate the larvicidal toxicity of different solvent extracts and essential oil of Karunochi, Vitex negundo (L.) on third instar larvae of the dengue vector, A. aegypti. The crude extracts were prepared by using soxhlet apparatus and rotary vacuum evaporator technique. The highest mortality was observed in essential oil and ethanolic extract followed by hexane and acetone extracts, the lethal concentrations LC50 (LC90) values were obtained from noticed, for Vn-EO- 218.46 (517.10), Vn-EE 268.37 (592.56), Vn-HE 309.59 (667.33), and Vn-AE 327.88 (748.47), respectively and nil mortality observed in the control treatment. Karunochi, V. negundo essential oil, and ethanolic extract (Vn-EE) were more efficient against A. aegypti than crude extracts of Vn-AE (acetone) and Vn-HE (hexane). Therefore, from our studies the formulations are promising for a low-cost larvicide without isolating an active ingredient, EO’s were tested. The goal of this study is to promote the use of plant-based larvicides in public health programmes.
 
Keywords: 
Vector Control; Biopesticides; Aedes aegypti; Vitex negundo; Larvicidal activity
 
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