Comparative laboratory diagnosis of malaria: Microscopy versus rapid diagnostic test kits in a tertiary institution of North-Central Nigeria
1 Department of Microbiology and Parasitology, College of Medicine and Allied Health Sciences, Bingham University, Jos Campus, Nigeria.
2 Department of Pharmacology and Therapeutics, College of Medicine and Allied Health Sciences, Bingham University, Jos Campus, Nigeria.
3 Department of Community Medicine, College of Medicine and Allied Health Sciences, Bingham University, Jos Campus, Nigeria.
4 Department of Haematology and Blood Transfusion, College of Medicine and Allied Health Sciences, Bingham University, Jos Campus, Nigeria.
Research Article
GSC Advanced Research and Reviews, 2022, 13(02), 145-149.
Article DOI: 10.30574/gscarr.2022.13.2.0319
Publication history:
Received on 03 October 2022; revised on 16 November 2022; accepted on 19November 2022
Abstract:
Laboratory diagnosis of malaria is a vital key for its effective management. Diagnosis of malaria includes rapid, sensitive, and specific test methods. This study was aimed to assess the diagnostic performance of PfHRP2 rapid malaria test with reference to light microscopy for the diagnosis of malaria at the Bingham University Teaching Hospital (BhUTH) Jos –Plateau State, Nigeria. A total of 150 febrile patients attending BHUTH who were sent to the Hospital Laboratory from the General out patients Department (GOPD) for malaria parasite test (MPT)request had their blood sample collected and tested for malaria parasites (MP) using Field Stain A and B stain microscopy and PfHRP2 rapid malaria test between September and November 2021.Results shows that the sensitivity and specificity of PfHRP2 rapid malaria were 9.23% and 90.0% respectively, with corresponding positive and negative predictive values (PPV) as 90.0%and (NPV) as13. 2%. PfHRP2 rapid malaria test showed good sensitivity and specificity that is in agreement with that of the reference light microscopy. The rapid diagnostic test (RDT) results compared well with the light microscopy (Gold standard) for Laboratory diagnosis for malaria. Sustained use of RDT as an alternative to light microscopy is recommended especially in malaria endemic areas and the rural communities where electricity is out of reach.
Keywords:
Malaria; HRP-2; Plasmodium falciparum; Sensitivity; Specificity; Comparison
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Copyright © 2022 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
