Contribution to the phytochemical study and evaluation of the antibacterial activity of extracts from the leaves of Ageratum conyzoides (Asteraceae) from Côte d'Ivoire

Souleymane Bamba 1, 2, Logopho Hyacinthe Ouattara 2, 3, *, Laciné Traoré 2, 4, Yapo Séverin Katou 2, 5, Lieuné Alexis Gué 2 and Guy Roger Mida Kabran 2

1 Environmental Sciences and Technologies Laboratory, UFR Environnement, Jean Lorougnon GUEDE University, Daloa, Ivory Coast.
2 Bio-Organic and Natural Substances Chemistry Laboratory, SFA UFR, Nangui ABROGOUA University, Abidjan, Ivory Coast
3 Organic Chemistry UPR, Mathematics-Physics-Chemistry Department, Biological Sciences UFR Peleforo GON COULIBALY University, Korhogo, Ivory Coast
4 UFR of Sciences and Technologies, University of Man, Man, Ivory Coast.
5 Department of Science and Technology, UFR Medical Sciences Université Alassane OUATTARA, 01 BPV. 18 Bouaké 01, Ivory Coast.
 
Research Article
GSC Advanced Research and Reviews, 2023, 17(03), 122–133.
Article DOI: 10.30574/gscarr.2023.17.3.0475
Publication history: 
Received on 06 November 2023; revised on 15 December 2023; accepted on 18 December 2023
 
Abstract: 
Ageratum conyzoïdes is a plant known for its therapeutic virtues. Its leaves are used by traditional healers to treat several pathologies. Phytochemical screening and quantitative analysis revealed the richness of this plant thanks to its multiple secondary metabolites. The aqueous, ethanolic and hexanic extracts were used for phytochemical screening. Thus, these extracts showed overall the presence of tannins, flavonoids, coumarins, free quinones, anthraquinones, alkaloids, sterols-triterpenes, terpenoids, saponosides, reducing compounds, anthocyanins, volatile oils and cardiac glycosides in the leaves of Ageratum conyzoïdes. Qualitative analysis by dosage showed that the ethanolic extract is more concentrated than the aqueous extract in total polyphenols, total flavonoids and total condensed tannins. The evaluation of the antibacterial activity of the ethanolic and aqueous extracts was carried out. It appears that only the ethanolic extract exhibits a bacteriostatic effect on the bacterial strain Staphylococcus aureus ATCC 25923.
 
Keywords: 
Ageratum conyzoïdes; Antibacterial activity; Phytochemical screeningCôte d’Ivoire
 
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