Correlation of nasopharyngeal carcinoma symptoms based on Digby’s score with biopsy results of nasopharyngeal masses of new patients in ENT-HNS clinic at prof. Dr. I.G.N.G Ngoerah State Hospital

Michael Christopher 1, *, Rovie Hikari Parastan 1, Jan Christian 1, Jonathan Setiawan 1 and I Gde Ardika Nuaba 2

1 Clinical Clerkship Medical Student, Faculty of Medicine, Udayana University, Indonesia.
2 Department of Ear Nose Throat – Head and Neck Surgery, Faculty of Medicine, Udayana University, Indonesia.
 
Research Article
GSC Advanced Research and Reviews, 2024, 18(01), 010–015.
Article DOI: 10.30574/gscarr.2024.18.1.0477
Publication history: 
Received on 06 November 2023; revised on 30 December 2023; accepted on 02 January 2024
 
Abstract: 
Introduction: Nasopharyngeal carcinoma is a disease that may cause mortality and shows with many clinical symptoms in the nose, ear, eyes, and nervous system. This study aimed to help clinical workers decide which patient with these symptoms must be referred or not.
Methods: Primary data from the ENT Clinic of Prof. Dr. dr. I.G.N.G Ngoerah was used from January 2022 to March 2022. Descriptive analysis and logistic regression were employed to describe the relationship between patients’ demographic, clinical symptoms with the diagnosis of NPC from histopathology examination.
Results: There are 40 patients in this study, with 22 patients have positive results of NPC, and 18 patients with negative results of NPC. Nasal mass, nasal symptoms and fulfillment of Digby’s score are the most related to NPC’s positive biopsy results (OR: 10, p=0.04; OR: 37. p=0,02; OR: 4.5, p=0,038 respectively).
Conclusion: NPC has wide variety of symptoms, and it must be kept in mind that these symptoms can be NPC and must consider to refer to ENT-HNS Specialist.
 
Keywords: 
Nasopharyngeal carcinoma; Digby’s score; NPC symptoms; Biopsy
 
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