Evaluation of analgesic and anti-inflammatory activities of ethanolic fruit extract of Terminalia chebula
Aditya College of Pharmacy, Department of Pharmacology, Surampalem, Kakinada District, Andhra Pradesh, India.
Research Article
GSC Advanced Research and Reviews, 2024, 18(02), 160–166.
Article DOI: 10.30574/gscarr.2024.18.2.0051
Publication history:
Received on 30 December 2023; revised on 07 February 2024; accepted on 09 February 2024
Abstract:
Analgesic and Anti-inflammatory activities of ethanolic fruit extract of Terminalia chebula was evaluated using tail-flick method, eddy’s hot plate method, acetic acid induced writhing responses and in-vivo anti-inflammatory property was determined using carrageenan rat paw edema. The ethanolic fruit extract of Terminalia chebula at different concentrations significantly inhibited the nociception in comparision with different standard drugs that showed anti-nociception. The test extract also reduced the edema induced in rats using carrageenan paw edema method as compared with the standard drug Diclofenac sodium 10mg/kg. The results obtained in this research study found to be very significant when compared to standard reference drug.
Keywords:
Terminalia chebula; Analgesic; Anti-inflammatory activity; Standard Reference Drugs
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
