Genetic factors in miscarriages

Ricardo A Galván-Márquez 1, *, Sebastián Díaz-Alanís 1, Paula V Lujan-Valles 1, Fernanda G Parra-García 1, Karla M Vázquez-Macias 1 and Brissia Lazalde 2

1 Faculty of Medicine and Nutrition, Universidad Juárez del Estado de Durango, Dgo., México.
2 Department of Genetics, Faculty of Medicine and Nutrition, Universidad Juárez del Estado de Durango, Dgo., México.
 
Review Article
GSC Advanced Research and Reviews, 2024, 21(03), 047–052.
Article DOI: 10.30574/gscarr.2024.21.3.0467
Publication history: 
Received on 20 October 2024; revised on 26 November 2024; accepted on 29 November 2024
 
Abstract: 
Miscarriage is defined as the unexpected loss of the pregnancy before the 20th week of gestation. The importance of this article is to acknowledge the varied genes involved in miscarriage, such as thrombophilia genes (factor 5 and factor 2); Immune-related genes (HLA-G and IL-10); and placental development genes (KIR genes).
 
Keywords: 
Miscarriage; Thrombophilia; Factor 5; Factor 2; HLA-G; KIR genes; IL-10
 
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