Giant cell lesions: A diagnostic mystery, case report and review of literature

Neeti Rajagopalan 1, *, Ramen Sinha 2, P Srinivas Reddy 1, Afroz Syed 2 and Anmol Agarwal

1 Oral and Maxillofacial Surgeon, Hyderabad, Telangana, India.
2 Department of Oral and Maxillofacial Surgery, Sri Sai College of Dental Surgery, Vikarabad, Telangana, India.
1Oral and Maxillofacial Surgeon, Hyderabad, Telangana, India.
2 Department of Oral Pathology, Sri Sai College of Dental Surgery, Vikarabad, Telangana, India.
3 Department of Oral and Maxillofacial Surgery, Institute of Dental Studies and Technology, Modinagar, Uttar Pradesh, India.
 
Case Study
GSC Advanced Research and Reviews, 2021, 07(02), 061–067.
Article DOI: 10.30574/gscarr.2021.7.2.0103
Publication history: 
Received on 03 April 2021; revised on 07 May 2021; accepted on 10 May 2021
 
Abstract: 
Giant cell lesions is a broad term encompassing a wide range of lesions that are biologically and morphologically diverse with an uncertain aetiology, whether it is a benign tumour, reactive lesion, inflammatory lesion or a self-healing lesion is ill understood. Their relation to each other also is not very clearly defined as they differ in their clinical and radiographic characteristics and their only similarity is in the histologic finding of non-neoplastic osteoclast like giant cells of different lineage. Owing to this fact their exact diagnosis continues to be one of the most obscure making them a dilemma, leaving many questions regarding their treatment and prognosis unanswered. Here we present a case of Central Giant Cell Tumor that was misdiagnosed as fibrous dysplasia that lead to an elusive treatment plan.
 
Keywords: 
Giant cell lesion; Biopsy; Multinucleated giant cell
 
Full text article in PDF: 
Share this