Neuromeningeal cryptococcosis (CNM) in an immunocompromised child

Nisrine Oudrhiri 1, *, Imane Rajil ², Kenza Barkate 3, Loubna Ait Said 1, Redouane. Moutaj 3, Noureddine Rada ² and Kaoutar Zahlane 1

1 Microbiology Laboratory Ibn Tofail Hospital, MOHAMMED VI University Hospital, Faculty of Medicine and Pharmacy. Marrakech, Morocco.
2 Pediatric Department, Arrazi Hospital, MOHAMMED VI University Hospital, Faculty of Medicine and Pharmacy. Marrakech, Morocco.
3 Mycology parasitology department, Avicenne Marrakech military hospital, Faculty of medicine and pharmacy. Marrakech, Morocco.
 
Case Study
GSC Advanced Research and Reviews, 2024, 19(02), 082–084.
Article DOI: 10.30574/gscarr.2024.19.2.0152
 
Publication history: 
Received on 12 March 2024; revised on 26 April 2024; accepted on 29 April 2024
 
Abstract: 
Background: Cryptococcal meningitis is one of the most common opportunistic infections in immunocompromised patients. Mostly it manifests as subacute/chronic meningitis, although pathological findings suggest extensive tissue invasion of the brain parenchyma and meninges. This disease has a very high mortality rate, even with the administration of an antifungal combination.
 
Keywords: 
Cryptococcus neoformans; Meningoencephalitis; Human immunodeficiency virus; Immunocompromised child
 
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