Phytochemical and antimicrobial screening of sitopaladi churna

Ekbote Maruthi T 1, *, Rajashekar KV 2, Shankarappa L 1 and Bharathi DR 3

1Department of Pharmacognosy, S.J.M. College of Pharmacy, Chitradurga-577502. Karnataka, India.
2 Departmentof Dravyagunavignana, Sri Raghavendra Ayurveda Medical College and Hospital, Malladihalli-577531.
3Department of pharmacology, S.J.M. College of Pharmacy, Chitradurga-577502. Karnataka, India.
 
Research Article
GSC Advanced Research and Reviews, 2019, 01(02), 016-019.
Article DOI: 10.30574/gscarr.2019.1.2.0011
Publication history: 
Received on 07 December 2019; revised on 19 December 2019; accepted on 22 December 2019
 
Abstract: 
Ayurvedic medicines are being used increasingly to fight or prevent common diseases. Sitopaladi churna is a polyherbal formulation containing Piper longum (Piperceae), Elettaria cardamom (Zingiberaceae), Cinnamomum zeylanicum (Lauraceae). Methanolic and Aqueous extracts of Sitopaladi Churna was screened for their antimicrobial activity against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Aspergillus niger and Candida albicans. The results of antimicrobial activity of Aqueous and Methanolic extracts of the Sitopaladi churna indicated that methanolic extract inhibited the growth of one or more test pathogens than aqueous extract. Sitopaladi churna formulation extracts showed a broad spectrum of antimicrobial activity. Phytochemical investigation revealed the presence of tannins, saponins, alkaloids, glycosides, flavonoids and triterpinoids. This may be due to the multifunctional effect of all the three plant ingredients of Sitopaladi churna.
 
Keywords: 
Sitopaladi Churna; Antimicrobial; Phytochemical
 
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