Proinflammatory cytokines in Parkinson’s disease and current treatment approaches
Elazığ Fethi Sekin City Hospital 23050-Elazığ, Turkey.
Review Article
GSC Advanced Research and Reviews, 2020, 02(01), 021-025.
Article DOI: 10.30574/gscarr.2020.2.1.0012
Publication history:
Received on 15 October 2019; revised on 17 December 2019; accepted on 23 December 2019
Abstract:
Parkinson's disease is a neurodegenerative disease characterized by progressive degeneration of dopaminergic neurons in the substantia nigra region. As the etiology is not clear, treatment in this disease is rather symptomatic and inadequate to prevent the progression of the disease. However, recent studies have demonstrated the strong association of neuroinflammation and proinflammatory cytokines with disease pathology. In this review, the relationship of proinflammatory cytokines with the pathology of Parkinson's disease is discussed and current treatment approaches targeting these mechanisms are evaluated.
Keywords:
Current approaches; Neurodegenerative disease; Neuroinflammation; Parkinson's disease; Proinflammatory cytokines
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Copyright © 2020 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
