A review on green tea catechins in Alzheimer’s disease of efficacy mechanism and future direction
1 Department of pharmacy shraddha institute of pharmacy kondala zambre, Washim, Maharashtra, India.
2 Department of Industrial Pharmacy shraddha institute of pharmacy kondala Zambre, Washim, Maharashtra, India.
3 Department of Pharmacology shraddha institute of pharmacy kondala Zambre, Washim, Maharashtra, India.
Review Article
GSC Advanced Research and Reviews, 2025, 22(01), 068-076.
Article DOI: 10.30574/gscarr.2025.22.1.0513
Publication history:
Received on 21 November 2024; revised on 01 January 2025; accepted on 03 January 2025
Abstract:
Alzheimer’s disease (AD) is a complex neurodegenerative disorder with limited treatment options. Green tea rich in catechins has been investigated for its potential neuroprotective and cognitive – enhancing effect. Oxidative stress is a component of the pathological mechanisms underlying AD. It is caused by a disruption of the balance between reactive oxygen species and antioxidant molecules. This imbalance also causes neuroinflammation. Catechins, which are bioactive components of tea, have antioxidative and anti-inflammatory effects. Moreover, other potential properties related to AD prevention and modification have been reported in in vitro and in vivo studies. Several clinical studies have also been conducted to date. The current review summarizes recent updates and perspectives of the effects of catechins on AD based on the molecular mechanisms and related clinical studies. This review examine the current evidence on green tea efficacy, mechanism and future direction in AD management.
Keywords:
Alzheimer’s disease; Catechin; Molecular Mechanisms; Clinical Study; Neuroprotection; Cognitive Enhancement
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Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
