Trends and morphologic variants of Kaposi Sarcoma as seen in Nnewi, Anambra State, Nigeria

Felix Emeka Menkiti 1, *, Cornelius Ozobia Ukah 1, Ifeoma Oluchukwu Menkiti 2, Chisom Godswill Chigbo 3 and Igwebuike Victor Onyiaorah 1

1 Department of Anatomic Pathology and Forensic Medicine, Nnamdi Azikiwe University, Nnewi Campus, Anambra state, Nigeria.
2 School of Nursing, Nnamdi Azikiwe University Teaching Hospitals, Nnewi, Anambra State, Nigeria.
3 Research society, Nnamdi Azikiwe University Teaching Hospitals, Nnewi, Anambra State, Nigeria.
 
Research Article
GSC Advanced Research and Reviews, 2022, 13(01), 125–132.
Article DOI: 10.30574/gscarr.2022.13.1.0269
Publication history: 
Received on 05 September 2022; revised on 10 October 2022; accepted on 13 October 2022
 
Abstract: 
Kaposi sarcoma (KS) is a human herpes virus type 8 (HHV-8) driven neoplasm with varying morphologic features and attendant diagnostic dilemma. This study presents the trend of KS in our environment and the different morphologic variants, with a view to arousing awareness and reducing missed and delayed diagnosis. KS accounted for 18.34% and 59.66% of vascular neoplasms and malignant vascular neoplasms, respectively with most KS occurring in the background of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS). The frequency peaked in 2013 and began to decline with a fairly even sex distribution. There are diverse variants of KS that can pose diagnostic challenges. Hence, there is need for this awareness to enhance prompt and accurate diagnosis. 
 
Keywords: 
Kaposi Sarcoma; Morphology; Trends; Variants; Vascular
 
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