Unusual presentation of a posterior mediastinal schwannoma associated with chest pain, cough and dyspnea

Manouchehr Aghajanzadeh 1, Alireza Jafarinezhad 2, Hamid Saeidi Saedi 3, Ali Talebi 4, Mahmode Khyabani 5, Omid Mosaffaee Rad 1, Zahra Sadin 6, Alireza shirzadi 7 and Mohaya Farzin 6, 8, *

1 Department of Thoracic Surgery, Guilan University of Medical Sciences, Rasht, Iran.
2 Department of Pulmonology, Guilan University of Medical Sciences, Rasht, Iran.
3 Department of Rdio-oncology, Guilan University of Medical Sciences, Rasht, Iran.
4 Department of Pathology, Guilan University of Medical Sciences, Rasht, Iran.
5 Department of Radiology, Guilan University of Medical Sciences, Rasht, Iran.
6 Inflammatory Lung Diseases Research Center, Department of Internal Medicine, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
7 Department of Anesthesiology, Negah Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
8 Department of Physiology, Razi Clinical Research Development Center, Guilan University of Medical Sciences, Rasht, Iran.
 
Case Study
GSC Advanced Research and Reviews, 2024, 21(02), 330–336.
Article DOI: 10.30574/gscarr.2024.21.2.0424
Publication history: 
Received on 29 September 2024; revised on 10 November 2024; accepted on 13 November 2024
 
Abstract: 
Neurogenic tumors (NT) are the most common of posterior mediastinal tumors, an 80% of all posterior mediastinal tumors are (NT). They originate from the spinal cord, sympathetic ganglia, or peripheral nerve roots. A Schwannoma is a slow-growing, encapsulated, and benign neurogenic tumor. Fewer than 9% of Schwannoma are located in the mediastinum. Posterior mediastinal Schwannoma originates from neural crest cells and typically from the intercostal nerves. Mediastinal Schwannoma is often asymptomatic but may present with unusual symptoms such as cough or dyspnea and hemoptysis because of pulmonary involvement. Although a definitive diagnosis is made by histopathology and immunohistochemically analysis, electron microscopy can be used to help item final diagnosis. We present a case of a benign posterior mediastinal Schwannoma, which is present in CXR and computed tomography (CT) imaging as a cystic lesion in a 58-year-old woman who was admitted to our hospital with back pain, cough, hemoptysis, and dyspnea.
 
Keywords: 
Schwannoma; Posterior mediastinal; Chest pain; Cough; Dyspnea
 
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Copyright information: 
Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0

 

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