From hair colour to diagnosis
1 Department of Dermatology and Venereology, Military Medical Academy, Sofia, Bulgaria.
2 Department of Infectious diseases, Parasitology and Dermatology, Faculty of Medicine, “Prof. Dr Paraskev Stoyanov”, Varna, Bulgaria.
Review Article
GSC Advanced Research and Reviews, 2021, 07(02), 068–072.
Article DOI: 10.30574/gscarr.2021.7.2.0107
Publication history:
Received on 10 April 2021; revised on 11 May 2021; accepted on 13 May 2021
Abstract:
Hair pigmentation contributes extremely to the visual appearance and human-to-human communication, thus exerting enormous sexual and social impact. Follicular melanogenesis depends on genetic, biochemical and physical phenomena as well as proper epithelial-melanocytic interaction. Shades of grey, yellow, brown, red, and black produced by melanin define the exact determination of hair colour. Versatile clinical conditions depend on genetic melanogenetic changes, pigment transfer to bulb keratinocytes defects and impaired signal transduction pathways. Herein, an update of recent scientific advances on follicular melanogenesis and its pathological-driven compartmental changes reflecting specific disease phenotypes, are presented.
Keywords:
Follicular melanogenesis; Skin colour changes
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Copyright © 2021 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
