An evaluation of sodium fluoride toxicity and the ameliorative potential of extract of Phyllantus amarus on reproductive hormones and lipid profile of adult male albino rats
Department of Applied Biochemistry, Faculty of Applied Natural Sciences, Enugu State University of Science and Technology, Enugu, Enugu State, Nigeria.
Research Article
GSC Advanced Research and Reviews, 2022, 10(03), 104–110.
Article DOI: 10.30574/gscarr.2022.10.3.0076
Publication history:
Received on 08 February 2022; revised on 11 March 2022; accepted on 13 March 2022
Abstract:
This study investigated the toxicity of sodium fluoride on male reproductive hormones and the ameliorative effects of extract of Phyllantus amarus on male reproductive hormones of adult albino rats. The study consisted of six equal groups of five albino rats that were administered with sodium fluoride and the Phyllantus amarus over a period of two weeks. The result indicates a possible toxicity of sodium fluoride on hormone and lipid profile and the probable capacity of the extract of Phyllantus amarus to ameliorate this toxicity.
Keywords:
Toxicity; Sodium fluoride; Reproductive; Hormones; Phyllantus amarus
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