The effect of feeding dried powder of Moringa oleifera leaves on total cholesterol level and antibody titer against Parvo virus in dogs

hay Kaoud Hussein Abdel; Mahmoud Iraqi Kassem; Mahmoud Khalil Maged

doi:10.30574/gscarr.2020.4.3.0074

Authors

hay Kaoud Hussein Abdel Department of Veterinary Hygiene and Environmental Pollution, Faculty of Veterinary Medicine, Cairo University, Egypt. Giza-Egypt, 12211.
Mahmoud Iraqi Kassem Department of Veterinary Hygiene and Environmental Pollution, Faculty of Veterinary Medicine, Cairo University, Egypt. Giza-Egypt, 12211.
Mahmoud Khalil Maged Department of Veterinary Hygiene and Environmental Pollution, Faculty of Veterinary Medicine, Cairo University, Egypt. Giza-Egypt, 12211.

DOI:

https://doi.org/10.30574/gscarr.2020.4.3.0074

Keywords:

Moringa oleifera, Total Cholesterol Level, Antibody Titer, Parvo Virus, Dogs

Abstract

The aim of this study was to determine the effect of feeding dried powder of Moringa oleifera leaves as a supplemented food on total cholesterol level and antibody titer against parvo virus in dogs. Moringa oleifera leaves were collected from Fayoum Province of Egypt. A total 12 weaned (45 days) German shepherd dogs divided into 4 groups in each group 3 Animals: 1^st as control, 2^nd 200 mg/kg, 3^rd 300 mg/kg and 4^th 400mg/kg of Moringa oleifera leaves powder. The blood samples were collected from dogs before, half and after experiment (0, 15, 30 days) for analysis of total cholesterol and anti-body titer against parvo virus. The results revealed that: (1) There is a significant decrease (P<0.05) in cholesterol level than normal range (135-278mg/dL) indicated that Moringa oleifera leaves may have a promising effect for cholesterol-lowering (2) Administration of the Moringa oleifera leaves lead to increase (P <0.05) in antibody titer against parvo virus in all groups compared to control group. Moringa oleifera as an immune boosting agent.

Metrics

Metrics Loading ...

References

Rosario SS, Aida Mallillin C, Trinidad P, Marco Trinidad P, de Leon P, Borlagdan Melissa B, Cid Kristine Bernadette S, Alcantara James David. Changes in Glucose, Lipid Profile after Consumption of Malunggay (Moringa oleifera) Leaves Products in Humans with Moderately Raised Serum Glucose and Cholesterol Levels. 2014; 4(4): 200-203.

Dangi SY, Jolly CI, Narayanan S. Antihypertensive activity of the total alkaloids from the leaves of Moringa oleifera. J. pharmaceutical biology. 2002; 40(2): 144-148.

S Ghasi, Nwobodo E, Ofili JO. Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high fat diet fed wistar rats. Journal of Ethnopharmacology. 2000; 69(1): 21-25.

Siddiqui S, Khan MI. Pharmacological study of Moringa pterygosperma. Central laboratories, Pakistan council of scientific and industrial research. 1968; 268-272.

Pankaj Jain Savita D, Patil G, Nitin, Girase Haswani V, Manoj J, Surana Sanjay. Hypolipidemic activity of Moringa oleifera Lam., Moringaceae, on high fat diet induced hyperlipidemia in albino rats. 2010, 20(6): 969-973.

Gaikwad SB, Mohan GK, Reddy KJ. Moringa oleifera leaves: immunomodulation in Wistar albino rats. Intl. J. Pharm. Pharm. Sci. 2011; 3(5): 426-430.

Ojeka SO, Obia O, Dapper DV. Effect of Acute Administration of Aqueous Leaf Extract of Moringa oleifera on Immunoglobulin levels in Wistar Rats. 2016; 14(4): 1-7.

Calis I, A,Yuruker A, Tasdemir D, Wright AD, Sticher O. Capabilities of aqueous leaf extract of Phyllanthusamarus in male Wistar Rats. Rep. Opin. 1997, 4(1): 22-37.

Gupta A, Gautam MK, Singh R, Kumar MV, Rao CV, Goel RK, Anupurba S . Immunomodulatory effect of Moringa oleifera Lam. extraction cyclophosphamide induced toxicity in mice. Indian J. Exp. Biol. 2010; 48(10): 1157-1160.

Tété-Bénissan A, Lawson-Evi K, Kokou K, Gbéassor M. Effect of Moringa oleifera lam. leaves powder on the evolution of hemogram profile in togolese undernourished children: evaluation on hiv-positive patients. 2012; 12 (No. 2), 1: 1486 5374.

Anjorin ST, Ikokoh PS, Okolo A. Mineral composition of antimicrobial activity of the compound isolated from chloroform extract of M. oleifera Lam. Pak. J. Biol. Sci. 2010; 22(5): 1888-1890.

Allain CC, Poon LS, Chan CSG, Richmond W, Fu PC. Enzymatic determination of total serum cholesterol.Clin Chem. 1974; 20: 470-475.

Waner et al. Vet. Record. 2003; 152: 588-591.

Neveda O, Asna U, Narayan PN. Effect of Dietary Lipids and Drumstick Leaves (Moringa oleifera) on Lipid Profile & Antioxidant Parameters in Rats. 2012; 3: 141-145.

Switi BG, Krishna M, Kavitha JR.. Moringa oleifera leaves: Immunomodulation in wistar albino rats, International Journal of Pharmacy and Pharmaceutical Sciences. 2011; 3: 426-430.

Obiazi HAK, Okwu G, Akpe AR, Omene OB. Effect of Moringa oleifera Leaf Extract on Immunoglobulins of Albino Wistar Rats. Index Copernicus Value. 2015; 78-96.

Obiazi HAK, GI, Okwu AR, Akpe Omene OB. Effect of Moringa oleifera Leaf Extract on Immunoglobulins of Albino Wistar Rats. International Journal of Science and Research (IJSR). 2017; 6 (5): 2708- 2711.