Imaging strategy for acute stroke patients, a review of literature

Authors

  • E. Radwan Moustafa Department of Radiology, Taibah University, Almadinah Almunawarah, Saudi Arabia

DOI:

https://doi.org/10.30574/gscarr.2021.6.1.0134

Keywords:

Stroke, Imaging Strategy, Wake-Up Stroke, Endovascular Treatment, cerebral Hemorrhage

Abstract

Background: This review article focused on the utilization and impact of current neuroimaging techniques for the patient with acute stroke, emphasizing how imaging builds upon clinical assessment to establish diagnosis or etiology and guide therapeutic decisions.

When requesting imaging examinations in patients with stroke symptoms; it is crucial to evaluate four significant parameters of stroke; parenchyma, vessels, perfusion, and penumbra. Evaluation of all these four parameters, in their right request are essential to grasp the explanation and potential therapy decisions for stroke in a specific patient. Extensive neurovascular imaging conventions utilizing multimodality CT (NCCT, CT Angiography, and CT Perfusion) or multimodality MRI (DWI-perfusion mismatch or DWI-FLAIR mismatch, and MR Angiography) might be utilized to evaluate the acute stroke patients and provide all the needed data for treatment of them inside minutes after the patient lands at the emergency clinic. Using this approach will help to discriminate between hemorrhagic and ischemic stroke as presence of frank intracerebral hemorrhage contraindicates reperfusion treatment, permits the choice of patients with large vessel occlusion for endovascular treatment and answer the important “tissue clock” within 6 hours from symptom and even with late-presenting (> 6 h) or wake-up stroke.

Conclusions: As patients with acute cerebral stroke might be critically ill, the initial imaging scanning for acute stroke patients should be constrained to the procurement of useful data only, considering the accessible therapeutic options at a given place at any given time.

Metrics

Metrics Loading ...

References

Menecie TI, Khedr SA-E-f, Hassan MAS, Zaghloul MHM. Role of susceptibility weighted imaging in acute ischemic stroke %J The Egyptian Journal of Hospital Medicine. 2019; 74(2):375-81.

Van der Zijden T, Mondelaers A, Yperzeele L, Voormolen M, Parizel PM. Current concepts in imaging and endovascular treatment of acute ischemic stroke: implications for the clinician. Insights Imaging. 2019; 10(1):64-73.

Hansen CK, Christensen A, Rodgers H, Havsteen I, Kruuse C, Christensen H. Does the Primary Imaging Modality-Computed Tomography or Magnetic Resonance Imaging-Influence Stroke Physicians' Certainty on Whether or Not to Give Thrombolysis to Randomized Acute Stroke Patients? J Stroke Cerebrovasc Dis. 2018; 27(4):926-35.

Thomalla G, Ebinger M, Fiehler J, Fiebach JB,Endres M, Gerloff C. EU-funded treatment study: WAKE-UP: a randomized, placebo-controlled MRI-based trial of thrombolysis in wake-up stroke. Nervenarzt. 2012; 83(10):1241-51.

Beauchamp NJ, Jr., Barker PB, Wang PY, vanZijl PC. Imaging of acute cerebral ischemia. Radiology. 1999; 212(2):307-24.

Rowley HA. The Four Ps of Acute Stroke Imaging: Parenchyma, Pipes, Perfusion, and Penumbra. American Journal of Neuroradiology. 2001; 22(4):599.

Christensen AF, Christensen H. Editorial: Imaging in Acute Stroke—New Options and State of the Art. Front Neurol. 2018; 8(736).

Culebras A, Kase CS, Masdeu JC, Fox AJ, Bryan RN, Grossman CB, et al. Practice guidelines for the use of imaging in transient ischemic attacks and acute stroke. A report of the Stroke Council, American Heart Association. Stroke. 1997; 28(7):1480-97.

Tan CO, Lam S, Kuppens D, Bergmans RHJ, Parameswaran BK, Forghani R, et al. Spot and Diffuse Signs: Quantitative Markers of Intracranial Hematoma Expansion at Dual-Energy CT. Radiology. 2019; 290(1):179-86.

Tong E, Hou Q, Fiebach JB, Wintermark M. The role of imaging in acute ischemic stroke. Neurosurg Focus. 2014; 36(1):E3-E.

Linfante I, Llinas RH, Caplan LR, Warach S. MRI features of intracerebral hemorrhage within 2 hours from symptom onset. Stroke. 1999; 30(11):2263-7.

Lin DD, Filippi CG, Steever AB, Zimmerman RD. Detection of intracranial hemorrhage: comparison between gradient-echo images and b(0) images obtained from diffusion-weighted echo-planar sequences. AJNR Am J Neuroradiol. 2001; 22(7):1275-81.

Toyoda K, Ida M, Fukuda K. Fluid-attenuated inversion recovery intraarterial signal: an early sign of hyperacute cerebral ischemia. AJNR Am J Neuroradiol. 2001; 22(6):1021-9.

Moustafa E.M. Radwan, Aboshaera KO. Magnetic resonance angiography in evaluation of acute intracranial steno-occlusive arterial disease. The Egyptian Journal of Radiology and Nuclear Medicine. 2016; 47(3):903-8.

Hwang DY, Silva GS, Furie KL, Greer DM. Comparative sensitivity of computed tomography vs. magnetic resonance imaging for detecting acute posterior fossa infarct. J Emerg Med. 2012; 42(5):559-65.

Pavlina AA, Radhakrishnan R, Vagal AS. Role of Imaging in Acute Ischemic Stroke. Semin Ultrasound CT MR. 2018; 39(5):412-24.

Young JY, Schaefer PW. Acute ischemic stroke imaging: a practical approach for diagnosis and triage. Int J Cardiovasc Imaging. 2016; 32(1):19-33.

Geijer B, Brockstedt S, Lindgren A, Ståhlberg F, Norrving B, Holtås S. Radiological diagnosis of acute stroke. Comparison of conventional MR imaging, echo-planar diffusion-weighted imaging, and spin-echo diffusion-weighted imaging. Acta Radiol. 1999; 40(3):255-62.

Flemming KD, Brown RD, Jr. Cerebral infarction and transient ischemic attacks. Efficient evaluation is essential to beneficial intervention. Postgrad Med. 2000; 107(6):55.

Perkins CJ, Kahya E, Roque CT, Roche PE, Newman GC. Fluid-attenuated inversion recovery and diffusion- and perfusion-weighted MRI abnormalities in 117 consecutive patients with stroke symptoms. Stroke. 2001; 32(12):2774-81.

Gomez CR, Schneck MJ, Biller J. Recent advances in the management of transient ischemic attacks. F1000Res. 2017; 6:1893-.

Ricci PE, Burdette JH, Elster AD, Reboussin DM. A comparison of fast spin-echo, fluid-attenuated inversion-recovery, and diffusion-weighted MR imaging in the first 10 days after cerebral infarction. AJNR Am J Neuroradiol. 1999; 20(8):1535-42.

Dankbaar JW, Bienfait HP, van den Berg C, Bennink E, Horsch AD, van Seeters T, et al. Wake-Up Stroke versus Stroke with Known Onset Time: Clinical and Multimodality CT Imaging Characteristics. Cerebrovasc Dis. 2018; 45(5-6):236-44.

Thomalla G, Boutitie F, Fiebach JB, Simonsen CZ, Nighoghossian N, Pedraza S, et al. Stroke With Unknown Time of Symptom Onset: Baseline Clinical and Magnetic Resonance Imaging Data of the First Thousand Patients in WAKE-UP (Efficacy and Safety of MRI-Based Thrombolysis in Wake-Up Stroke: A Randomized, Doubleblind, Placebo-Controlled Trial). Stroke. 2017; 48(3):770-3.

Swan JS, Sainfort F, Lawrence WF, Kuruchittham V, Kongnakorn T, Heisey DM. Process utility for imaging in cerebrovascular disease. Acad Radiol. 2003; 10(3):266-74.

Klufas RA, Hsu L, Barnes PD, Patel MR, Schwartz RB. Dissection of the carotid and vertebral arteries: imaging with MR angiography. AJR Am J Roentgenol. 1995; 164(3):673-7.

Katz DA, Marks MP, Napel SA, Bracci PM, Roberts SL. Circle of Willis: evaluation with spiral CT angiography, MR angiography, and conventional angiography. Radiology. 1995; 195(2):445-9.

Spies JB. Complications of Diagnostic Arteriography. Semin intervent Radiol. 1994; 11(02):93-101.

Qureshi AI, Isa A, Cinnamon J, Fountain J, Ottenlips JR, Braimah J, et al. Magnetic resonance angiography in patients with brain infarction. J Neuroimaging. 1998; 8(2):65-70.

Paciaroni M, Caso V, Agnelli G. The concept of ischemic penumbra in acute stroke and therapeutic opportunities. Eur Neurol. 2009; 61(6):321-30.

Heit JJ, Wintermark M. Perfusion Computed Tomography for the Evaluation of Acute Ischemic Stroke: Strengths and Pitfalls. Stroke. 2016; 47(4):1153-8.

Cosnard G, Duprez T, Grandin C, Dechambre S, Mataigne F, Smith A. Diffusion- and perfusion-weighted MR imaging during the hyperacute phase of stroke. J Radiol. 2000; 81(8):858-69.

Schaefer PW, Ozsunar Y, He J, Hamberg LM, Hunter GJ, Sorensen AG, et al. Assessing tissue viability with MR diffusion and perfusion imaging. AJNR Am J Neuroradiol. 2003; 24(3):436-43.

Shih LC, Saver JL, Alger JR, Starkman S, Leary MC, Vinuela F, et al. Perfusion-weighted magnetic resonance imaging thresholds identifying core, irreversibly infarcted tissue. Stroke. 2003; 34(6):1425-30.

Butcher K, Parsons M, Baird T, Barber A, Donnan G, Desmond P, et al. Perfusion thresholds in acute stroke thrombolysis. Stroke. 2003; 34(9):2159-64.

Copen WA, Rezai Gharai L, Barak ER, Schwamm LH, Wu O, Kamalian S, et al. Existence of the diffusion-perfusion mismatch within 24 hours after onset of acute stroke: dependence on proximal arterial occlusion. Radiology. 2009; 250(3):878-86.

Darby DG, Barber PA, Gerraty RP, Desmond PM, Yang Q, Parsons M, et al. Pathophysiological topography of acute ischemia by combined diffusion-weighted and perfusion MRI. Stroke. 1999; 30(10):2043-52.

Uno M, Harada M, Yoneda K, Matsubara S, Satoh K, Nagahiro S. Can diffusion- and perfusion-weighted magnetic resonance imaging evaluate the efficacy of acute thrombolysis in patients with internal carotid artery or middle cerebral artery occlusion? Neurosurgery. 2002; 50(1):28-35.

Downloads

Published

2021-01-30

How to Cite

Moustafa, E. R. (2021). Imaging strategy for acute stroke patients, a review of literature. GSC Advanced Research and Reviews, 6(1), 037–046. https://doi.org/10.30574/gscarr.2021.6.1.0134

Issue

Section

Original Article