Dennettia tripetala (Pepper Fruit), a review of its ethno-medicinal use, phyto-constituents, and biological properties

Dauda Muhammed; Yetunde H. Adebiyi; Bernard O. Odey; Rahmatallah A. Alawode; Abdullateef Lawal; Banke Mary Okunlola; Jonathan Ibrahim; Eustace Bonghan Berinyuy

doi:10.30574/gscarr.2021.6.3.0024

Authors

Dauda Muhammed Southern Guinea Research Station-Forestry Research Institute of Nigeria, Mokwa, Niger State, Nigeria.
Yetunde H. Adebiyi Department of Biochemistry, Federal University of Technology, Minna, Nigeria.
Bernard O. Odey Trial Afforestation-Research Station, Forestry Research Institute of Nigeria (FRIN), Afaka-Kaduna State, Nigeria.
Rahmatallah A. Alawode Southern Guinea Research Station-Forestry Research Institute of Nigeria, Mokwa, Niger State, Nigeria.
Abdullateef Lawal Department of Chemistry, University of Ilorin, Nigeria.
Banke Mary Okunlola Department of Microbiology, Federal University of Technology Minna, Nigeria.
Jonathan Ibrahim Gombe State College of Health Science and Technology, Kaltungo, Nigeria.
Eustace Bonghan Berinyuy Faculty of Medicine and Biomedical Science, University of Yaounde 1, Cameroon.

DOI:

https://doi.org/10.30574/gscarr.2021.6.3.0024

Keywords:

Dennettia tripetala, Ethno-medicine, Phyto-constituents, Biological properties

Abstract

There has been tremendous growth in field of herbal medicine as therapeutic agents. Dennettia tripetala, is known to possess ethnomedicinal properties and has been used for centuries in the Ayurvedic system of medicine for the treatments of various diseases. The present review provides detailed description on the distribution, ethno-medicinal use, phyto-constituents, and biological properties of the plant that justifies its use as a potential therapeutic agent in management of different diseases. The phyto chemical composition of Dennettia tripetala include alkaloids, tannins, saponins, flavonoids, terpenoids, steroids and cardiac glycosides while it biological activities include antioxidant, antidiabetic, antibacterial, antihypertensive, anticonvulsant, antitrypanosomal, antimalarial, anti-inflammatory and cytotoxic properties among others. In conclusion, Dennettia tripetala contains various nutritional and phytochemicals compositions that make it valuable for pharmacological purposes.

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