Effect of preprocedural oral rinses with active ingredients like chlorhexidine, povidone-iodine and cetylpyridinium chloride in neutralizing SARS-COV-2 concentration in aerosol

Authors

  • Gurman Preet Singh Department of Periodontology, Mathrusri Ramabai Ambedkar Dental College and Hospital, Bangalore, Karnataka, India.
  • Lalith Vivekan Department of Periodontology, Mathrusri Ramabai Ambedkar Dental College and Hospital, Bangalore, Karnataka, India.
  • Priyankar Roy Department of Periodontology, Mathrusri Ramabai Ambedkar Dental College and Hospital, Bangalore, Karnataka, India.

DOI:

https://doi.org/10.30574/gscarr.2021.6.3.0048

Keywords:

Neutralize, Oral Rinses, SARS-COV-2, Aerosols, COVID-19

Abstract

The havoc of COVID 19 pandemic, has created a situation of panic among the health care professionals and general population worldwide. The Virus being a droplet infection has increased the vulnerability of infection among the dental professionals, affecting the clinical practice. The patient being reluctant to visit the dentist due to fear of cross contamination in the dental office has reduced the patient in flow to a certain extent. Various measures have been suggested by the health authorities to avoid the transmission of the virus in the dental office. One such measure is the use of a preprocedural rinse. This acts as the need of the hour to reduce the virus transmission from the patients and prevent cross contamination in dental clinics. Various formulation of mouthwashes are used for preprocedural rinsing. The most common being chlorhexidine, povidone-iodine, cetypyridinium chloride and hydrogen peroxide. The antimicrobial property of these have also been found to be effective against severe acute respiratory syndrome corona virus 2.  These ingredients in mouth washes are found to temporarily neutralize the virus load for certain amount of time in saliva and other oral fluids. Thus preprocedural rinse can reduce the risk of transmission of virus and can be used as an adjunct with air filters and PPE kits for prevention and protection from infection.

Metrics

Metrics Loading ...

References

World Health Organization timeline of response to COVID-19. July 30 2020.

Transmission of SARS-Cov-2: implications for infection prevention precautions by World health organization. July 09, 2020.

Bernstein D, G Schiff et al. In vitro virucidal effectiveness of a 0.12%-chlorhexidine gluconate mouthrinse. J Dent. Res. 1990 Mar; 69(3): 874-6.

Colgate Laboratory Tests Shows Toothpaste and mouthwash neutralize 99.9% virus that causes covid-19, Thomas dipiazza, Colgate- Palmolive Company. 212-310-2607.

Gary Wong, Yu-Hai Bi et al. Zoonotic origins of human coronavirus 2019(HCoV-19/ SARS-CoV-2): why is this work important? Zool Res. 2020 May; 41(3): 213-219.

ACE-2 receptors of SARS CoV-2, R&D systems of biotechne brand.

Van Doremalen N, Bushmaker, Dylan H Morris et al. Aerosol and surface stability of SARS-COV-2 as compared with SARS-COV-1. N Engl J Med. 2020 April; 382: 1564-1567.

Singh A, Manjunath RS, Singhla D, Bhattacharya HS, Sarkar A, Chandra N. Aerosol, a health hazard during ultrasonic scaling: A clinic-microbiological study. Indian J Dent Res. 2016; 27: 160-2.

American Dental Association: oral health topics -Mouthwash.

Vanessa Costa Marui et al. Efficacy of preprocedural mouthrinses in the reduction of microorganisms in aerosol: A systemic review J Am Dent Assoc. 2019 Dec; 150(12): 1015-1026.e1.

Avinash S, Bidra et al. rapid in-vitro inactivation of severe acute respiratory syndrome corona virus 2 (SARS-COV-2) using povidone-iodine oral antiseptic rinse .J Prosthodont. 2020 Jul; 29(6): 529-533.

Hassandarvish P, Tiong V, et al. Povidone iodine gargle and mouthwash.Br Dent J. 2020; 228, 900.

Povidone-Iodine information from drugs update.

Colgate Laboratory Tests Shows Toothpaste and mouthwash neutralize 99.9% virus that causes covid-19, Thomas dipiazza, Colgate- Palmolive Company. 212-310-2607.

Newman and Carranza’s, Clinical Periodontology, 3rd South Asia Edition. India: Relx Pvt. Ltd. 2019.

Yoon JG, Yoon J et al. Clinical Significance of a High SARS-CoV-2 Viral Load in the Saliva. J Korean Med Sci. 2020 May 25; 35(20): e195.

DH Fine, D Furgang et al. Reduction of viable bacteria in dental aerosols by preprocedural rinsing with an antiseptic mouthrinse. Am J Dent. 193 oct; 6(5): 219-21.

Downloads

Published

2021-03-30

How to Cite

Singh, G. P., Vivekan, L., & Roy, P. (2021). Effect of preprocedural oral rinses with active ingredients like chlorhexidine, povidone-iodine and cetylpyridinium chloride in neutralizing SARS-COV-2 concentration in aerosol. GSC Advanced Research and Reviews, 6(3), 132–135. https://doi.org/10.30574/gscarr.2021.6.3.0048

Issue

Section

Review Article

Most read articles by the same author(s)