Thorax imaging of vaccinated and non-vaccinated Covid-19 patients, how are they different?

Abstract

Covid-19 is a global pandemic which currently becomes the world's concern. There were various studies to overcome the problem of high mortality due to the infection of the SARS Cov-2 virus. Vaccine is one of the solutions to lessen the global burden. Vaccine is expected to produce immunity for community health. The scientists are investigating the effectiveness of the vaccine. Some vaccinated Covid-19 patients can still be infected by the virus even with moderate or severe symptoms. Chest x-ray is one of the modalities to see clinical progress. This study aims to compare the chest x-ray of hospitalized patients who have been vaccinated and those who have not. There were two groups of 60 hospitalized patients aged 18-50 years, namely the vaccinated and non-vaccinated groups. Patients with type II diabetes mellitus, hypertension, heart failure or autoimmune disease were excluded from the sample. Assessment of severity level through chest x-ray was done by calculating Brixia score. The calculation of Brixia score was carried out by three researchers having parallel levels of competence with a tolerance of differences of less than 5%. Bivariate analysis was conducted to compare Brixia scores between the two groups. A total of 8 male (26,7%) and 22 female (73,3%) patients in the vaccinated group had lower Brixia scores with a mean score of 1,53 + 1,27 compared to 30 patients (60% male, 40% female) in the non-vaccinated group with a mean of 6,0 + 2,61 and p value of 0.001. There were no death cases in all samples. There is a difference in the average Brixia score with a lower tendency of severity in the vaccinated group compared to the non-vaccinated group. Vaccine is useful for raising immunity so that it avoids severe conditions due to the SARS Cov-2 virus infection