Exploring the role of gut microbiota in human health
1 Department of Applied Microbiology and Brewing, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria.
2 Department of Veterinary Medicine, Michael Okpara University of Agriculture, Umudike, Nigeria.
3 Department of English Language and Literature, Nnamdi Azikiwe University, Awka, Nigeria.
4 School of Biomedical Science, College of Art and Sciences, Kent State University, Ohio, USA.
Review Article
GSC Biological and Pharmaceutical Sciences, 2024, 27(01), 051–059.
Article DOI: 10.30574/gscbps.2024.27.1.0100
Publication history:
Received on 09 February 2024; revised on 31 March 2024; accepted on 03 April 2024
Abstract:
The study explores the intricate relationship between the human gut microbiota and health. It analyzes the gut microbiota’s roles in digestion, metabolism, immune responses, and overall well-being. The review discusses the composition and diversity of gut microbial communities, emphasizing their symbiotic relationship with the host. It also examines how gut dysbiosis, or microbial imbalance, relates to health conditions like inflammatory bowel diseases and metabolic disorders. The review highlights research methodologies like metagenomics and metabolomics that deepen our understanding of gut microbiota function. It also explores external factors, such as diet and antibiotic use, in shaping the gut microbiome. The review discusses potential therapeutic interventions like probiotics and fecal microbiota transplantation, suggesting a future for personalized medicine. By synthesizing existing knowledge, the review aims to advance understanding of the gut microbiota’s role in health and suggest future research and interventions.
Keywords:
Dysbiosis; Gut microbiota; Human health; Microbiome; Therapeutic interventions
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Copyright information:
Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
