Effects of discriminate and indiscriminate use of enrofloxcin on hematological parameters

Md. Mominul Islam Bhuiyan; Md. Shafiqul Islam; Md. Rakibul Hasan; Kazi Rafiqul Isla

doi:10.30574/gscarr.2021.7.1.0064

Authors

Md. Mominul Islam Bhuiyan Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.
Md. Shafiqul Islam Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.
Md. Rakibul Hasan Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.
Kazi Rafiqul Isla Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.

DOI:

https://doi.org/10.30574/gscarr.2021.7.1.0064

Keywords:

Enrofloxacin, Hematological parameters, PCV, TEC, Hb

Abstract

Hematological indication is an important finding for pathophysiology analysis of biological science. This study was designed with the aim to investigate the effects of residual antibiotics on hematological parameters of broiler following discriminate and indiscriminate use. 18 broiler DOC (Cobb-500) were reared up to 31 days. On day 16, they were randomly divided into 3 groups, namely Group–A (Control group), Group-B (Discriminate group) and Group-C (Indiscriminate group). Each group contains 6 birds. The discriminate and indiscriminate group was treated with antibiotic, enrofloxacin. In Group-B withdrawal period was followed and treatment was stopped before 7 days of sacrifice. On the other hand, withdrawal period was not maintained in indiscriminate group and the antibiotic treatment was continued until the day of sacrifice. The Total erythrocyte count (million/mm3) of control, discriminate, and indiscriminate groups were 3.15±0.047, 2.66±0.091, and 2.90±0.11 respectively. The Hb (gm%) of control, discriminate, and indiscriminate groups were 8.17±0.07, 7.37±0.09, and 7.28±0.07 respectively. The Packed Cell Volume (%) of control, discriminate, and indiscriminate group were 24.17±0.48, 23.17±0.48, and 22.33±0.67 respectively. There was no significant difference on blood parameter found among the groups. Therefore, discriminate and indiscriminate use of enrofloxacin has no bad effect on hematological parameters of broiler.

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