Gene expression and its application in biotechnology

Luka Yelwa  Barde; Hussaini  Adamu; Grace Ifemedike  Uzoma; Mohammed  Bello; Mohammed Abba  Danjuma

doi:10.30574/gscarr.2021.8.1.0093

Authors

Luka Yelwa Barde African Centre of Excellence for Neglected Tropical Diseases and Forensic Biotechnology, Zaria Kaduna State. Nigeria.
Hussaini Adamu Department of Biology Umar Suleiman College of Education Gashua, Yobe State, Nigeria.
Grace Ifemedike Uzoma Department of General Studies Education Umar Suleiman College of Education Gashua, Yobe State, Nigeria.
Mohammed Bello Department of Biology Umar Suleiman College of Education Gashua, Yobe State, Nigeria.
Mohammed Abba Danjuma Department of Biology Umar Suleiman College of Education Gashua, Yobe State, Nigeria.

DOI:

https://doi.org/10.30574/gscarr.2021.8.1.0093

Keywords:

Gene expression, Application, Biotechnology, Bioengineering

Abstract

Advances in biotechnology has been the subject of praise for a decade now, this is due to techniques such as gene expression which has contributed immensely in the success of genetic engineering, medical advancement, vaccine production and agriculture. Gene expression has become a very important tool for the overall improvement of quality of life. This paper tries to look into the development of gene expression in the last forty years and to highlight how technological advancements in the study of gene expression brought about improvements as a focal point. Technological advancements associated with northern blotting, western blotting, and enzyme-linked immunosobent assays, Polymerase Chain Reaction (PCR) technology with emphasis on quantitative PCR, differential protein display technique and DNA sequencing and hybridization arrays technology with emphasis on macroarrays and microarrays in facilitating gene expression will be discussed.

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