61-year-old man with intestinal amyloidosis: A case report
Surgical Pathology Department, Santo Spirito Hospital, Casale Monferrato, Viale Giolitti 2, Italy.
Case Study
GSC Biological and Pharmaceutical Sciences, 2020, 11(03), 185-188.
Article DOI: 10.30574/gscbps.2020.11.3.0164
Publication history:
Received on 05 June 2020; revised on 16 June 2020; accepted on 19 June 2020
Abstract:
Gastrointestinal amyloidosis (GIA), a protein deposition disorder, represents a complex common pathway that encompasses multiple etiologies and presentations. It is characterized by accumulation of insoluble extracellular protein fragments that have been rendered resistant to digestion. The most common form of systemic amyloidosis in the Western world is AL, in which the fibrils derive from monoclonal immunoglobulin light chains. Its incidence is approximately 10 cases / million / year with an average age at diagnosis of around 60 years. Herein, we report a case of 61-year-old man with colic AL amyloidosis.
Keywords:
Amyloidosis; Protein deposition; Colon; Monoclonal immunoglobulin
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Copyright © 2020 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
