Albumin levels, mean platelet volume, and neutrophil lymphocyte ratio as predictors of COVID-19 outcomes
1 Department of Internal Medicine, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia.
2 Department of Internal Medicine, Dr. Moewardi Hospital, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia.
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 22(01), 096-104.
Article DOI: 10.30574/gscbps.2023.22.1.0493
Publication history:
Received on 20 November 2022; revised on 07 January 2023; accepted on 10 January 2023
Abstract:
Coronavirus Disease 2019 (COVID-19) is a respiratory infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. COVID-19 spreads very quickly to various countries and causes a high mortality rate. According to this urgency, a study was conducted on albumin levels, mean platelet volume (MPV), and neutrophil-lymphocyte ratio (NLR) as predictors of COVID-19 outcome. This research was an analytic observational study conducted cross-sectional at Dr. Moewardi Hospital Surakarta, Indonesia, from June-October 2021. Data analysis used the logistic regression test and ROC analysis to determine the cut-off point for each variable. The total samples used in this study were 123 samples, with 68 survival patients and 55 nonsurvival patients. Logistic regression test results received p values for MPV and NLR, respectively, 0.048 and 0.001, and OR values 1.369 and 1.186 with Nagelkerke R Square 0.186. The cut-off point of MPV is 9.05 (sensitivity 76.4%; specificity 48.5%; p=0.019), and the cut-off point of NLR is 3.27 (sensitivity 92.7%; specificity 55.9%; p=0.001). In conclusion, MPV and NLR can be used as predictors of COVID-19 outcomes.
Keywords:
COVID-19; Predictors of Outcomes; Albumin Levels; Mean Platelet Volume (MPV); Neutrophil Lymphocyte Ratio (NLR)
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
