Anti-inflammatory activity Keelvayu nivarana churnam in carrageenan induced inflammatory rats
Department of Siddha Medicine, Tamil University, Thanjavur, Tamil Nadu, S. India.
Research Article
GSC Biological and Pharmaceutical Sciences, 2018, 05(01), 017–020
Article DOI: 10.30574/gscbps.2018.5.1.0084
Publication history:
Received on 17 August 2018; revised on 08 September 2018; accepted on 12 September 2018
Abstract:
Anti-inflammatory activity of Keelvayu nivarana churnam in carrageenan induced inflammatory rats was evaluated. Keelvayu nivarana churnam at the doses of 10, 15 mg/kg and 25 mg/kg of body weight in experimental animals. Anti-inflammatory activity was evaluated by Carrageenan induced paw edema in rats. Indomethacin (3 mg/Kg body weight) was employed as standard drug. Animals were randomized into 4 group (n = 6). Control group receives vehicle only. Keelvayu nivarana churnam treated with high dose which produced significant inhibition of edema and pain. This study confirms Keelvayu nivarana churnam possesses significant anti-inflammatory efficacy.
Keywords:
Anti-inflammatory activity; Keelvayu nivarana churnam; Carrageenan; Indomethacin
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