Antibacterial activity of methanol leaf extract and fruit decoction from Morinda persicifolia Buch. – Ham
Faculty of Natural Science Pedagogy, Sai Gon University, 273 An Duong Vuong Street, Ward 3, District 5, Ho Chi Minh City, Vietnam.
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 23(03), 054–059.
Article DOI: 10.30574/gscbps.2023.23.3.0218
Publication history:
Received on 22 April 2023; revised on 31 May 2023; accepted on 02 June 2023
Abstract:
The study investigated antibacterial potentials of Morinda persicifolia Buch. – Ham collected from Lang Sen Wetland Reserve, Long An Province in Vietnam. Antimicrobial activity of M. persicifolia Buch. – Ham was evaluated based on size of antibacterial zone of methanol leaf extract by agar well diffusion method, values of minimum inhibitory concentration (MIC) by micro-well dilution method, minimum bactericidal concentration (MBC) by spread plate method and MBC/MIC ratios of fruit decoction against five test bacteria. The results showed that the methanol leaf extract produced growth inhibition zones against test bacteria with diameters of smaller than 6 mm (2.41 mm -5.63 mm). The fruit decoction had MIC of 100 mg/mL for P. aeruginosa and 200 mg/mL for B. cereus, B. subtilis, S. aureus and E. coli; and MBC about 300 mg/mL to B. cereus and E. coli and 400 mg/mL to B. cereus, B. subtilis, S. aureus and P. aeruginosa. MBC/MIC ratios of the fruit decoction against test bacteria were from 1.5 to 4. Thus, the methanol leaf extract was considered antibacterial at weak level and the fruit decoction was considered bactericidal.
Keywords:
Antibacterial Activity; Fruit decoction; Growth inhibition zones; MBC/MIC; Methanol leaf extract; Morinda persicifolia Buch – Ham
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
