Antibacterial test of ethanol extract of "Cocor-Bebek" leaves (Kalanchoe pinnata) against the growth of Staphylococcus aureus and Salmonella typhi

I Putu Sudayasa 1, *, Gusti Ayu Kumala Dewi 2, Shally Ariasnitra 2, Yenti Purnamasari 3 and La Ode Alifariki 4

1 Public Health Sciences-Community Medicine, Faculty of Medical, Halu Oleo University, Indonesia.
2 Medical Undergraduate Study Program, Faculty of Medical, Halu Oleo University, Indonesia.
3 Biomedical Laboratories, Faculty of Medical, Halu Oleo University, Indonesia.
4 Department of Epidemiology, Faculty of Medical, Halu Oleo University, Indonesia.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2022, 19(03), 204–212.
Article DOI: 10.30574/gscbps.2022.19.3.0226
Publication history: 
Received on 07 May 2022; revised on 14 June 2022; accepted on 16 June 2022
 
Abstract: 
This study aims to determine the antibacterial effect of the Ethanol Extract of Cocor bebek leaves (Kalanchoe pinnata) on the growth of Staphylococcus aureus and Salmonella typhi. The study is a true experimental, using a posttest only control group design with the independent variable being the extract of cocor bebek leaves (Kalanchoe pinnata). This study found that extracts of cocor bebek leaves (Kalanchoe pinnata) with a concentration of 7.5% and 15% had no inhibitory power, while at concentrations of 30% and 60% had weak inhibitory power as the minimum inhibitory power, and a concentration of 100% had inhibitory power, and strong on the growth of Staphylococcus aureus bacteria. Meanwhile for the growth of Salmonella typhi, a concentration of 7.5% from 3 repetitions had an average inhibition zone of 1.2 mm. for a concentration of 15% has an average inhibition zone diameter of 3 repetitions of 2.2 mm. concentration of 30% from 3 rolls has an average inhibition zone of 12.6 mm. for a concentration of 60% has an average inhibition zone of 3 repetitions of 19.8mm. There is antibacterial activity of ethanolic extract of cocor bebek leaf (Kalanchoe pinnata) against the growth of Staphylococcus aureus and Salmonella typhi.
 
Keywords: 
Antibacterial Agents; Ethanol; Salmonella Typhi; Staphylococcus Aureus
 
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