Antifungal activity of chromatographic fractions of hexane extract x 1-2 of Eucalyptus torelliana (Corymbia torelliana) on the in vitro growth of candida albicans candida tropicalis and candida glabrata

Josette Don AGRE 1, *, Rolland Gueyraud KIPRE 1, Frédéric Kra KOUAME 2, Eric-Kévin Gbouhoury BOLOU 2 and ET Joseph Allico DJAMAN 1

1 Laboratory of Biology and Health, UFR Biosciences, Félix HOUPHOUET-BOIGNY University, Côte d’Ivoire.
2 National Center of Floristics, Félix HOUPHOUËT-BOIGNY University, Côte d’Ivoire.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2022, 20(01), 277–283.
Article DOI: 10.30574/gscbps.2022.20.1.0293
Publication history: 
Received on 10 June 2022; revised on 16 July 2022; accepted on 18 July 2022
 
Abstract: 
In developing countries (DC), general mortality is mainly due to infectious diseases which outweigh cardiovascular and degenerative diseases as well as cancers. Among these, opportunistic candidiasis is on the rise among HIV/AIDS patients. AIDS remains the leading cause of death in young adults in developing countries. In view of the growth of infectious diseases, our research team tested the chromatographic fractions of the X1-2 Eucalyptus torelliana extract (ornamental plants) on the in vitro growth of candida albicans, candida tropicalis and candida glabrata. Among these fractions, fraction F5 showed the best activity on the three germs tested with a CMF value of 62.5 µg/mL for each germ.
 
Keywords: 
Chromatography; Infectious diseases; Candidiasis; Eucalyptus torelliana
 
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