Antifungal and antioxidant activities of Carapa procera oil and its physicochemical characteristics

Serges Gbamelé Kouakou Kan 1, Guillaume Yayé Yapi 2, *, Valerie Bonouman Ira Ama 3, Maurice Anigbé Amon 1, Olivier Chatigre Kouamé 1 and Joseph Djaman Allico 1, 3

1 Université Félix Houphouët-Boigny (UFHB) Abidjan Cocody, 22 BP 582 Abidjan 01.
2 Heath Biology, Université Jean Lorougnon Guédé (UJLoG) Daloa, Bp 150 Daloa.
3 Institut Pasteur de Côte d’Ivoire (IPCI), 01 BP 490 Abidjan 01.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2020, 10(02), 130-137.
Article DOI: 10.30574/gscbps.2020.10.2.0025
Publication history: 
Received on 27 January 2020; revised on 14 February 2020; accepted on 17 February 2020
 
Abstract: 
Carapa procera oil is traditionally used for various pathologies including dermatoses. This study evaluates two the method of extraction of oil. The physicochemical characteristics, the antioxidant activity, and the antifungal properties were conducted respectively according to the ISO methods, DPPH method, and disc method plates while a phytochemical screening was performed by the colouring method, and the Thin Layer Chromatography (TLC). The results revealed that the iodine, saponification and refraction index vary from 68.50 to 73.11 gI2/100 g, 197.70 to 198 mgKOH/g and 1.46 respectively. The antioxidant activity ranged from 715.8 to 115.3 mg/mL and the inhibition diameters on the fungal germs revealed 18 to 21 mm for Candida albicans strains and 23 to 25 mm for Trichophytic isolates. The presence of terpenoids, flavonoids, sterols and alkaloids have been proven. The extraction solvent assisted method retain the antioxidant activity and antifungal activity.
 
Keywords: 
Oil; Antifungal; Antioxydant; Physicochemical Characteristics; Screening
 
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