Antimicrobial screening of the crude extract of Hannoa klaineana against some pathogens
1 Department of Pharmacognosy and Traditional Medicine, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria.
2 Department of Applied Sciences, Faculty of Applied Sciences and General Studies, Federal College of Dental Technology and Therapy, Trans-Ekulu, Enugu State, Nigeria.
3 Department of Pharmacognosy and Environmental Medicine, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria.
Research Article
GSC Biological and Pharmaceutical Sciences, 2020, 12(01), 249-254.
Article DOI: 10.30574/gscbps.2020.12.1.0233
Publication history:
Received on 20 July 2020; revised on 29 July 2020; accepted on 30 July 2020
Abstract:
Hannoa klaineana is an ever green plant belonging to the Simaroubaceae family commonly known as Oghuru in Igbo, itekiri in Edo and igi gun in Yoruba. It has been used in ethnomedicine for the treatment of malaria, cough, and stomach problems. The present study assessed the antimicrobial property of the extract of H. klaineana against Staphylococcus aureus, Salmonella typhi, Escherichia coli, Pseudomonas aeruginosa, Bacilus substilus, and Candida albicans using the agar diffusion method. Our preliminary phytochemical studies showed the presence of resins, steroids, terpenoids, glycosides, alkaloids, flavonoids, tannins, saponins, and phenols. Quantitative determination of the phytochemicals present revealed alkaloids (1.2%), tannins (11.2%), flavonoids (3%), saponins (29.3%), and phenolic compounds (45.7%). The extract of H. klaineana showed good antimicrobial activity against C. albicans and moderate active against S. aureus, S. typhi, E. coli, P. aeruginosa, B. substilus. These results further confirm the potentials of Nigerian plants as a source of bioactive compounds with pharmaceutical, agricultural or industrial applications.
Keywords:
Antimicrobial; Phytochemical; Bacteria; Fungi; Hannoa klaineana.
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Copyright © 2020 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
