Antioxidant, antibacterial activities and phytochemical screening of Asteriscus pygmaeus aerial parts ethanolic extract
Chemistry of Tanning Materials and Leather Technology Department, National Research Centre, Dokki, Cairo, Egypt.
Research Article
GSC Biological and Pharmaceutical Sciences, 2019, 09(03), 041-046.
Article DOI: 10.30574/gscbps.2019.9.3.0218
Publication history:
Received on 20 November 2019; revised on 12 December 2019; accepted on 13 December 2019
Abstract:
Phytochemical investigation of the Aerial parts of Asteriscus pygmaeus ethanolic extract gave rise to isolation of a new compound: 6-Hydroxykaempferol 6-methylether (eupafolin) -4' glucopyranoside (1) together with eight known metabolites; patuletin 7-glucoside (2), chrysoeriol 7- O- glucoside (3), 6-Hydroxy kaempferol (4), 6-Hydroxy kaempferol 6-methyl ether (eupafolin) (5), 6,4` dimethoxy luteolin (6), patuletin (7), chrysoeriol (8) and luteolin (9). Their structures were established by chromatographic methods, chemical degradation and various spectroscopic data; compared with previously known analogues. Antioxidant activity of ethanolic extract was investigated using DPPH (2,2-diphenyl-1-picrylhydrazyl) as stable radicals method indicated a high radical scavenging activity for it. The results for antimicrobial study for extract against bacteria and fungi showed that it exhibited broad spectrum of antimicrobial activity against gram positive bacteria, gram negative bacterial and fungal cultures.
Keywords:
Asteraceae; Asteriscus pygmaeus; flavonoids, Antioxidant; Antibacterial activities
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Copyright © 2019 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
