Bergenia ciliata as antibacterial agent

Sayed Suliman Shah 1, †, Dawood Shah 1, Ibrahim Khan 2, *, †, Muhammad Ilyas 3, Sohail Ahmad Jan 4 and Imran Khan 1

1 Department of Chemistry, Government Degree College No.2 Mardan, Abdul Wali Khan University Mardan, KP Pakistan.
2 Department of Biotechnology, School of Life Sciences and Technology, University of Electronic Science and Technology of China.
3 Department of Botany, Bacha Khan University Charsadda, KP Pakistan.
4 Department of Biotechnology, Hazara University Mansehra, KP Pakistan.
First and third author contributed equally to this work.
 
Review Article
GSC Biological and Pharmaceutical Sciences, 2020, 12(02), 037-045.
Article DOI: 10.30574/gscbps.2020.12.2.0206
Publication history: 
Received on 28 June 2020; ; revised on 03 August 2020; accepted on 05 August 2020
 
Abstract: 
The search for alternatives to combat antibiotics has been increased due to the upsurge in cases of antibiotic-resistant pathogens that has become a global phenomenon which threatens the human health. Medicinal plants provide multiple health benefits because these plants contain bioactive phytochemicals that are used in medicines as alternatives to various ailments of human beings. Bergenia ciliata is a perennial herb belongs to the family Saxifragaceae that consists of about 30 genera and 580 species worldwide. It has large, evergreen and leathery leaves with the pink to dark purple flowers and has various traditional and modern medical uses. This plant is considered is one of the most effective antibacterial agents. The present review emphasizes the antibacterial potential of Bergenia ciliata by compiling various researches and fragmented information. The most important phytochemicals derived from Bergenia ciliata launched on the pharmaceutical market are also discussed. This attempt will help the researchers to develop and synthesize new antibacterial drugs from Bergenia ciliata against drug-resistive pathogens.
 
Keywords: 
Bergenia ciliata; Antibacterial agent; Drug-resistive pathogens; Pharmacology; Bioactive compounds
 
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