Blood donation type and hepatitis B and C seroepidemiology at Hôpital Sominé DOLO de Mopti
1 Centre National de Recherche Scientifique et Technologique, Biomedical laboratory, Hôpital Sominé DOLO de Mopti, Mopti, Mali.
2 Université des Sciences Techniques et Technologiques de Bamako, Faculty of pharmacy, Bamako, Mali.
3 Centre National de Recherche Scientifique et Technologique, Medicine, Hôpital Sominé DOLO de Mopti, Mopti, Mali.
4 Centre National de Recherche Scientifique et Technologique, Public Health, Hôpital Sominé DOLO de Mopti, Mopti, Mali.
Research Article
GSC Biological and Pharmaceutical Sciences, 2020, 13(03), 025-031.
Article DOI: 10.30574/gscbps.2020.13.3.0393
Publication history:
Received on 20 November 2020; revised on 29 November 2020; accepted on 03 December 2020
Abstract:
Background: The increasing prevalence of hepatitis viral markers in developing countries results in a concern in the setting of blood transfusion safety. The aim of this study was to assess the prevalence of hepatitis viral markers among blood donors and their link with sociodemographic factors.
Methods: We performed a retrospective study on blood donors screened for HBV and HCV. HBV and HCV serologies were performed by immunochromatographic methods using Alere DetermineTM HBs-Ag and SD BIOLOLINETM HCV-Ab. Data were analyzed by R 3.4.3. The logistic regression was fitted in univariate and multivariate analysis.
Results: A total of 11,372 donors were enrolled. The overall prevalence was 10.4%. The specific prevalence of HBV and HCV were 8.9% and 1.5% respectively. The co-infection rate was 0.3%. HBV seropositivity proportion was significantly higher in family donors compared to volunteer (9.8% vs 6,0%, or = 1.71 [1.30-2.29] p < 0,001). HBV seropositivity was positively influenced by male sex aOR = 1.77 [1.4-2.26], p < 0.001 and unemployed aOR = 1.20 [1.03-1.40], p = 0.02 in multivariate analysis.
Conclusion: Our data suggest that voluntary donors and particularly female which had an occupation had a lower prevalence of hepatitis viral markers.
Keywords:
Blood donation; Hepatitis; Seroepidemiology; Hôpital Sominé DOLO de Mopti.
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Copyright © 2020 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
