Chemo-profiling and assessment of antioxidant activity and antibacterial potentials of selected plants of family Combretaceae

Das Arundhati 1, *, Samal Kailash Chandra 2 and   Bastia Akshaya Kumar 1

1Department of Botany, North Orissa University, Sriram Chandra Vihar, Takatpur, Baripada, Mayurbhanj, Odisha.
2Department of Agril. Biotechnology, College of Agriculture, OUAT, Bhubaneswar-751003, Odisha.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2020, 10(02), 030-039.
Article DOI: 10.30574/gscbps.2020.10.2.0016
Publication history: 
Received on 21 January 2020; revised on 30 January 2020; accepted on 01 February 2020
 
Abstract: 
Traditional medicine is used all over the world, especially in developing countries. Though synthetic drugs are very effective but are harmful to human beings because of their side effects. Genus of Terminalia and Combretum species belongs to the family Combretaceae, which contains 20 genera and 600 species as herbs, shrubs, and trees. These plants are used in different traditional medicine for their antioxidant property and also for the treatment of hepatitis and malaria due to the presence of antibacterial properties. The present study is focused on chemo- profiling, screening of the antioxidant compound, antioxidant activities and antimicrobial properties of different Terminalia and Combretum species, namely Terminalia arjuna, T. alata, T. bellerica, T. cataappa, T. chebulla, T. bucera and T. mauritiana,, Combretum albidum, C. roxburghii  and C. indicum. Four different concentrations (20, 40, 60 and 80 mg/ml) of methanolic extracts of leave and bark of these plant species were tested against six bacterial pathogens i.e Streptococcus epidermis, Salmonella enterica, Staphylococcus aureus, Escherichia coli, Bacillus subtillis and Pseudomonas aeruginosa using disc diffusion method. It was observed that the methanolic leaf and bark extract T. arjuna, T. chebulla, and C. albidum proved remarkable antibacterial properties against the different bacterial strains. This study will help to know the properties of medicinal plants for making different formulation of different types of green medicine.
 
Keywords: 
Antibacterial assay; Antioxidant; Chemo-profiling; Combretum species. HPTLC; Terminalia spp.
 
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