Chitosan nanoparticles: Current aspects

Prasad R Deshmukh 1, *, Dipti Bonde 1, Dipti Ruikar 1 and Somashekhar Khadabadi 2

1 Department of Pharmaceutics, P. R. Pote Patil College of Pharmacy, Amravati, Maharashtra, India.
2 Government College of Pharmacy, Amravati, Maharashtra, India.
 
Review Article
GSC Biological and Pharmaceutical Sciences, 2022, 21(03), 001–013.
Article DOI: 10.30574/gscbps.2022.21.3.0456
Publication history: 
Received on 22 October 2022; revised on 29 November 2022; accepted on 02 December 2022
 
Abstract: 
Nanoparticles are currently becoming one of the important parts for various segments. Much more process/application becomes effective or more economical and time-saving because of nanoparticles. Polymers with distinct characteristics are widely used but nature-origin polymer has important properties that make a polymeric material for nanoparticles. Many methods were successfully evaluated to prepare chitosan nanoparticles for loading various compounds including ionotropic gelation, micelles, and emulsification methods. In this article, we have reviewed the current aspects made-up of chitosan nanoparticles. Chitosan nanoparticles have an application to improve bioavailability, controlled release of the loaded drug also increases cellular uptake and targeting to cancer cells, stabilization of proteins, and enhanced the effectivity of anti-microbial agents. In agriculture, chitosan nanoparticles are used for herbicides, insecticides, and pesticide loading to improve the cultivation of crops and are used in food packaging. Chitosan nanoparticles also have wide applications as implant and therapeutic agent.
 
Keywords: 
Chitosan; Nanoparticles; Pharmaceutical application; Agriculture; Implants
 
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